منابع مشابه
Anti-TNF-Alpha Therapy and Systemic Vasculitis
TNF-α is a pleiotropic cytokine, which plays a major role in the pathogenesis of numerous autoimmune and/or inflammatory systemic diseases. Systemic vasculitis constitutes a group of rare diseases, characterized by inflammation of the arterial or venous vessel wall, causing stenosis and thrombosis. Treatment of the different type of vasculitis mainly relies on steroids and immunosuppressive dru...
متن کامل[Anti-TNF therapy and cancer].
Tumor necrosis factor (TNF) is implicated in the control of tumoral growth in addition to the systemic inflammatory response. TNF blockage produces a comprensible reservation in patients with risk factors for cancer. No clear evidence for this came out from pre-clinical or clinical trials. Biosafety registries established in the post-marketing phase have concluded that, in general, cancer cases...
متن کاملAnti-TNF-α therapy in membranous glomerulonephritis
A 43-year-old woman with a history of psoriasis vulgaris was admitted for nephrotic syndrome that had started 6 months before. Renal biopsy revealed membranous glomerulonephritis (MGN). She did not receive any therapy for MGN. Two months later she started therapy for psoriasis with adalimumab, which resulted in disappearance of psoriatic skin lesions with progressive reduction of 24h proteinuri...
متن کاملAnti-TNF-α Therapy for Ankylosing Spondylitis
BACKGROUND This review evaluated the safety and efficacy of etanercept in patients with ankylosing spondylitis (AS). METHODS Of 59 patients with AS, this study reviewed 11 patients who were refractory to conventional therapy and treated with etanercept from September 2005 to January 2008. The mean follow-up duration was 13.6 months. The general improvement was evaluated by the Bath Ankylosing...
متن کاملSerum Tumor Necrosis Factor Alpha (TNF-Α) Levels after Anti-Tuberculous Therapy
The monocyte/macrophage-derived cytokine, Tumor Necrosis Factor Alpha (TNF-α) plays a central role in effective granulomatous immunity to Mycobacterium tuberculosis infections in humans. The present study was conducted to document changes in the serum TNF-α level of patients after varying durations of anti-tuberculous therapy as compared to normal healthy controls. A comparative study was condu...
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ژورنال
عنوان ژورنال: DMW - Deutsche Medizinische Wochenschrift
سال: 2004
ISSN: 0012-0472,1439-4413
DOI: 10.1055/s-2004-829005